
Taccalonolide A NEW
Price | $110 |
Package | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-02 |
Product Details
Product Name: Taccalonolide A | CAS No.: 108885-68-3 |
Purity: 99.4% | Supply Ability: 10g |
Release date: 2025/05/02 |
Product Introduction
Bioactivity
Name | Taccalonolide A |
Description | Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells. |
Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 60 mg/mL (85.38 mM), Sonication is recommended. |
Keywords | Taccalonolide A | P-gp | MicrotubuleAssociated | Microtubule/Tubulin | Microtubule Associated | microtubule | Inhibitor | inhibit | Caspase | Bcl-2 | Apoptosis |
Inhibitors Related | Stavudine | 5-Fluorouracil | Acetylcysteine | Myricetin | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Metronidazole | Tributyrin | L-Ascorbic acid sodium salt | Salicylic acid |
Related Compound Libraries | Anti-Tumor Natural Product Library | Apoptosis Compound Library | Bioactive Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Microtubule-Targeted Compound Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Covalent Natural Product Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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