Sultopride hydrochloride NEW
| Price | $40 | $89 | $143 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Sultopride hydrochloride | CAS No.: 23694-17-9 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Sultopride hydrochloride |
| 描述 | Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist for dopamine D2 and D3 receptors. |
| 體內(nèi)活性 | Sultopride and sulpiride are both chemically similar benzamide derivatives and selective antagonists of dopamine D2 receptors.?However, these drugs differ in clinical properties.?We compared the effects of sultopride and sulpiride on dopamine turnover in rats following the administration of these drugs alone or in combination with apomorphine.?The administration of sultopride or sulpiride markedly accelerated dopamine turnover in the rat brain.?The increase in the level of dopamine metabolites in the striatum was more marked in the sultopride-treated rats.?Sulpiride affected the limbic dopamine receptors preferentially, whereas sultopride affected the striatal and the limbic dopamine receptors equally.?A low dose of apomorphine induced a reduction in the concentration of dopamine metabolites in the striatum and the nucleus accumbens by approximately 55%, but not in the medial prefrontal cortex.?Sultopride was more effective in preventing an apomorphine-induced reduction in dopamine metabolite levels. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (127.90 mM) |
| 關(guān)鍵字 | dopamine | Sultopride | Sultopride hydrochloride | Dopamine Receptor | LIN 1418 Hydrochloride | LIN-1418 | LIN 1418 | HVA | LIN1418 | Inhibitor | striatum | LIN1418 Hydrochloride | LIN-1418 Hydrochloride | receptor | inhibit | DOPAC | Sultopride Hydrochloride | levels |
| 相關(guān)產(chǎn)品 | CLOZAPINE N-OXIDE | Octopamine hydrochloride | Oxolinic acid |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 神經(jīng)退行性疾病化合物庫 | 神經(jīng)信號(hào)分子庫 | 膜蛋白靶向化合物庫 | 抑制劑庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 | 抗COVID-19化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1520.00/25mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-23 | |
| $20.00/1kg |
VIP3Y
|
Hebei Fengjia New Material Co., Ltd
|
2023-03-30 | |
| $0.00/1kg |
VIP3Y
|
Wuhan Senwayer Century Chemical Co.,Ltd
|
2022-10-28 | |
| $1.10/1g |
VIP4Y
|
Dideu Industries Group Limited
|
2021-07-23 | |
| $1.00/1KG |
VIP5Y
|
Career Henan Chemical Co
|
2019-12-24 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY