Sultopride hydrochloride NEW
| Price | $40 | $89 | $143 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Sultopride hydrochloride | CAS No.: 23694-17-9 |
| Purity: ≥95% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Sultopride hydrochloride |
| Description | Sultopride hydrochloride (LIN-1418 hydrochloride) is a selective antagonist for dopamine D2 and D3 receptors. |
| In vivo | Sultopride and sulpiride are both chemically similar benzamide derivatives and selective antagonists of dopamine D2 receptors.?However, these drugs differ in clinical properties.?We compared the effects of sultopride and sulpiride on dopamine turnover in rats following the administration of these drugs alone or in combination with apomorphine.?The administration of sultopride or sulpiride markedly accelerated dopamine turnover in the rat brain.?The increase in the level of dopamine metabolites in the striatum was more marked in the sultopride-treated rats.?Sulpiride affected the limbic dopamine receptors preferentially, whereas sultopride affected the striatal and the limbic dopamine receptors equally.?A low dose of apomorphine induced a reduction in the concentration of dopamine metabolites in the striatum and the nucleus accumbens by approximately 55%, but not in the medial prefrontal cortex.?Sultopride was more effective in preventing an apomorphine-induced reduction in dopamine metabolite levels. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (127.90 mM) |
| Keywords | dopamine | Sultopride | Sultopride hydrochloride | Dopamine Receptor | LIN 1418 Hydrochloride | LIN-1418 | LIN 1418 | HVA | LIN1418 | Inhibitor | striatum | LIN1418 Hydrochloride | LIN-1418 Hydrochloride | receptor | inhibit | DOPAC | Sultopride Hydrochloride | levels |
| Inhibitors Related | CLOZAPINE N-OXIDE | Octopamine hydrochloride | Oxolinic acid |
| Related Compound Libraries | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-COVID-19 Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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