Sulfaguanidine NEW
| Price | $78 |
| Package | 5g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Sulfaguanidine | CAS No.: 57-67-0 |
| Purity: 99.74% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Sulfaguanidine |
| Description | Sulfaguanidine (Guanicil), a sulfonamide, is served as an anti-infective agent. |
| In vitro | Adult rats exhibit a more robust elimination capability for Sulfaguanidine when compared to neonatal rats. Pharmacokinetic studies of gastrointestinal absorption reveal that, following oral administration, the peak plasma concentration in adult rats is significantly lower than that in neonatal rats, although there is no marked difference in the time taken to reach peak blood levels. The absolute bioavailability in adult rats (12.76%) is approximately one-fifth that of neonatal rats (57.86%). In adults, the plasma elimination of Sulfaguanidine, administered intravenously at doses of 2.5 or 25 mg/kg, can be described by a two-compartment open model. Conversely, the plasma concentration profile of Sulfaguanidine, post oral administration of 25 mg/kg, is consistent with a one- or two-compartment open model. Consequently, Sulfaguanidine is less readily absorbed in adult rats, while neonatal rats demonstrate effective absorption. |
| In vivo | Sulfaguanidine, one of the earliest sulfa drugs employed in the treatment of intestinal infections, effectively inhibits the synthesis of nutritional factors in intestinal bacteria. It also efficiently impedes the growth of Gram-negative enterobacteria. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 55 mg/mL (256.71 mM) |
| Keywords | Inhibitor | inhibit | dysentery | enteric | bacillary | antimicrobial,antibiotic | Sulfaguanidine | sulfonamide | Bacterial | Antibiotic | infections |
| Inhibitors Related | Neomycin sulfate | Stavudine | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Hydroxychloroquine | Guanidine hydrochloride | Doxycycline | Paeonol | Naringin | Dimethyl sulfoxide | Salicylic acid |
| Related Compound Libraries | Bioactive Compound Library | Antibiotics Library | Drug Repurposing Compound Library | Drug-Fragment Library | NO PAINS Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Human Metabolite Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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