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Postion:Product Catalog >SPP-86
SPP-86
  • SPP-86

SPP-86 NEW

Price $41 $97 $155
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-08

Product Details

Product Name: SPP-86 CAS No.: 1357349-91-7
Purity: 98.19% Supply Ability: 10g
Release date: 2024/11/08

Product Introduction

Bioactivity

名稱SPP-86
描述SPP-86 is an effective and selective cell-permeable inhibitor of RET tyrosine kinase with an IC50 of 8 nM.
體外活性Administration of SPP-86 (0-10 μM) suppresses RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling and estrogen receptorα (ERα) phosphorylation in MCF7 cells. Administration of SPP-86 (0-10 μM) also supppresses MAPK signaling and proliferation in RET/PTC1 expressing TPC1 compared to 8505C or C643 cells [1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (360.59 mM), Sonication is recommended.
關(guān)鍵字SPP 86 | Inhibitor | inhibit | RET | SPP86 | SPP-86
相關(guān)產(chǎn)品Cabozantinib | Fedratinib | Regorafenib monohydrate | Regorafenib Hydrochloride | SGI-7079 | Regorafenib | AST 487 | Amuvatinib | ON123300 | Lenvatinib mesylate | Lenvatinib | Selpercatinib
相關(guān)庫細(xì)胞凋亡化合物庫 | 經(jīng)典已知活性庫 | 激酶抑制劑庫 | 酪氨酸激酶分子庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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