SP-13786 NEW
Price | $67 | $177 | $277 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: SP-13786 | CAS No.: 1448440-52-5 |
Purity: 99.52% | Supply Ability: 10g |
Release date: 2024/11/18 |
Product Introduction
Bioactivity
Name | SP-13786 |
Description | SP-13786 is an inhibitor of fibroblast activation protein (FAP) and prolyl oligopeptidase (PREP) with IC50 values ??of 3.2 nM and 1.8 μM, respectively. |
In vivo | METHODS: SP-13786 (UAMC-1110) (20 mg/kg, orally, twice a day) was used to treat Panc02-SIY cell tumor xenograft mice, and its effect on tumors in the mice was observed. RESULTS Tumor-infiltrating macrophages were reduced during UAMC-1110 administration, and UAMC-1110 significantly increased tumor-infiltrating CD8 T cells, including effector subsets. [2] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 100 mg/mL (290.43 mM), Sonication is recommended. |
Keywords | SP13786 | UAMC 1110 | SP-13786 | SP 13786 | UAMC1110 |
Related Compound Libraries | 經(jīng)典已知活性庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫 | 共價(jià)抑制劑庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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