Solamargine NEW
| Price | $54 | $117 | $177 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Solamargine | CAS No.: 20311-51-7 |
| Purity: 99.88% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱(chēng) | Solamargine |
| 描述 | Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cells. |
| 體外活性 | Solamargine concentration-dependently reduced HepG2 cell viability. Solamargine (7.5 μM) reduced cell viability by less than 20% in HepG2 cells. Solamargine (highest dose) decreased cell invasion and migration by more than 72% and 70% in HepG2 cells, respectively. Solamargine reduced function and expression of MMP-2/9 proteins. Solamargine time-dependently increased phosphorylation of p38 mitogen-activated protein kinase (p38 MAPK) in a fashion. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 91 mg/mL (104.8 mM) |
| 關(guān)鍵字 | Apoptosis | Inhibitor | cytotoxicity | cells | Cluster of differentiation 243 | MDR1 | Pgp | P-glycoprotein | ABCB1 | inhibit | Solamargine | cancer | gastric | delta-Solanigrine | Multidrug resistance protein 1 | P-gp | CD243 | HepG2 |
| 相關(guān)產(chǎn)品 | Stavudine | 5-Fluorouracil | Myricetin | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid |
| 相關(guān)庫(kù) | 疼痛相關(guān)化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 膜蛋白靶向化合物庫(kù) | 生物堿類(lèi)天然產(chǎn)物庫(kù) | 植物來(lái)源化合物庫(kù) | 天然產(chǎn)物庫(kù) | 中藥抗炎分子庫(kù) | 抗衰老化合物庫(kù) | 離子通道庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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