SIB-1553A hydrochloride NEW
Price | $93 | $235 | $378 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-20 |
Product Details
Product Name: SIB-1553A hydrochloride | CAS No.: 191611-89-9 |
Purity: 99.71% | Supply Ability: 10g |
Release date: 2024/11/20 |
Product Introduction
Bioactivity
Name | SIB-1553A hydrochloride |
Description | SIB-1553A hydrochloride is an orally available, selective nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand.SIB-1553A hydrochloride enhances cognition and may be useful in the study of Alzheimer's disease and cognitive impairment. |
In vitro | In calcium flux assays, compared to nicotine, SIB-1553A hydrochloride (0.1-5 μM) exhibits higher selectivity in both potency and efficacy towards β4 subunits containing recombinant hnAChRs (α2β4, α3beta4, and α4β4) over β2 subunits containing nAChRs (α4β2 and α3beta2)[1]. |
In vivo | In Male Sprague-Dawley rats (200-250 g), SIB-1553A hydrochloride (1, 2, 4, 10, 20, and 40 mg/kg; s.c) induced hippocampal ACh release[2]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | H2O : H2O: 20 mg/mL (73.04 mM) |
Keywords | SIB-1553A | SIB1553A | SIB 1553A |
Inhibitors Related | Adiphenine hydrochloride | Nanofin | Forskolin | Pilocarpine Hydrochloride | (+)-Sparteine | Pilocarpine nitrate | CLOZAPINE N-OXIDE | Ribavirin | Adenine | Amitriptyline hydrochloride | Choline chloride | Propoxur |
Related Compound Libraries | Bioactive Compound Library | Neurotransmitter Receptor Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$1980.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$0.00/1kg |
VIP3Y
|
Wuhan Senwayer Century Chemical Co.,Ltd
|
2022-10-28 | |
$0.00/1KG |
Shanxi Lianxu New Material Co., LTD
|
2023-04-28 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY