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Postion:Product Catalog >API>Nervous system drugs>Antidepressants, Antimanics drugs>Sertraline hydrochloride
Sertraline hydrochloride
  • Sertraline hydrochloride

Sertraline hydrochloride

Price $610
Package 1kg
Min. Order: 0.1kg
Supply Ability: 20 tons
Update Time: 2024-09-25

Product Details

Product Name: Sertraline hydrochloride CAS No.: 79559-97-0
EC-No.: 616-702-0 Min. Order: 0.1kg
Purity: 99% min Supply Ability: 20 tons
Release date: 2024/09/25

Product name: Sertraline hydrochloride

CAS No.: 79559-97-0

Molecular formula: C17H18Cl3N

Molecular weight: 342.69

Melting point: 246-249°C

 

Sertraline hydrochloride is a selective serotonin reuptake inhibitor. Its mechanism of action is related to its inhibition of central neuron serotonin reuptake. At clinical doses, sertraline blocks the uptake of serotonin by human platelets. Research suggests that sertraline is a potent and selective neuronal serotonin reuptake inhibitor, with only a weak effect on norepinephrine and dopamine. In vitro studies have shown that sertraline has effects on adrenergic receptors (α1, α2, β), cholinergic receptors, GABA receptors, dopaminergic receptors, histamine receptors, serotoninergic receptors (5HT1A, 5HT1B, 5HT2) or benzodiazepine receptors have no obvious affinity. The antagonism to the above-mentioned receptors is believed to be related to the sedation, anticholinergic effect and cardiotoxicity of other psychiatric drugs. Long-term administration of sertraline to animals can down-regulate norepinephrine receptors in the brain, which is consistent with the effects of other clinical antidepressants. Sertraline has no inhibitory effect on monoamine oxidase.

Company Profile Introduction

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

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  • Since: 2022-10-21
  • Address: Wanda global centur, Wuhan China
INQUIRY

+86-13627115097
market02@senwayer.com