Product Details
Product Name:
Schisandrol B |
CAS No.:
58546-54-6 |
Purity:
99.32% |
Supply Ability:
10g |
Release date:
2024/11/13 |
Product Introduction
Bioactivity
名稱 | Schisandrol B |
描述 | 1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has anti-inflammatory property, potentially result from the inhibition of COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation. 3. Schisandrol B induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. 4. Schisandrol B significantly inhibits cell proliferation in a dose-dependent manner, due to cell cycle arrest in the G1 phase with the downregulation of cyclin D1 expression and Retinoblastoma (RB) phosphorylation. |
存儲條件 | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (120.06 mM)
|
關(guān)鍵字 | antioxidant | Hepato-protective | BCL-2 | inhibit | P-glycoprotein | Inhibitor | CYP3A11 | Autophagy | anti-inflammatory | CCND1 | Reactive Oxygen Species | CYP2E1 | TJN101 | anti-diabetic | Schisandrol B | p53 | lignan | TJN 101 | p21 | CYPs | Cytochrome P450 | Gomisin-A | PCNA |
相關(guān)產(chǎn)品 | Stavudine | Aceglutamide | Sodium 4-phenylbutyrate | L-Ascorbic acid | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Valproic Acid | Curcumin | Paeonol | Naringin | Gefitinib |
相關(guān)庫 | 中藥單體化合物庫 | 藥物功能重定位化合物庫 | 中藥抗炎分子庫 | 抑制劑庫 | 煙草單體化合物庫 | 神經(jīng)保護化合物庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 古代經(jīng)典名方目錄分子庫 | 抗癌藥物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:96996-50-8
$42.00 / 1mg
-
CAS:16891-54-6
$415.00 / 1mg
-
CAS:2098376-42-0
$758.00 / 1mg
Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$0.00/20mg |
VIP3Y
|
Changsha Staherb Natural Ingredients Co., Ltd.
|
2022-10-13 |
|
$0.00/20mg |
|
Shanghai Standard Technology Co., Ltd.
|
2019-11-15 |
|
$1.00/1KG |
VIP7Y
|
Career Henan Chemical Co
|
2019-07-12 |