Salvianolic acid B NEW
Price | $60 | $210 |
Package | 5mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-11 |
Product Details
Product Name: Salvianolic acid B | CAS No.: 121521-90-2 |
Purity: 99.86% | Supply Ability: 10g |
Release date: 2024/11/11 |
Product Introduction
Bioactivity
名稱 | Salvianolic acid B |
描述 | Salvianolic acid B is a water-soluble antioxidant from Salvia extract. Salvianolic acid B plays significant role of antioxidant effect; antiplatelet aggregation, anticoagulant, and antithrombotic effect. |
體外活性 | METHODS: Rat brain microvascular endothelial cells rCMECs were pretreated with Salvianolic acid B (0-100 μM) for 30 min and incubated with H2O2 (200 μM) for 12 h. Apoptosis was detected by TUNEL assay. RESULTS: Salvianolic acid B pretreatment dose-dependently reduced H2O2-induced apoptosis. [1] METHODS: Mouse primary hepatic stellate cell HSCs were treated with Salvianolic acid B (10 μmol/L) for 48 h. Cell proliferation was detected by MTT assay. RESULTS: Cells treated with Salvianolic acid B significantly reduced cell proliferation at 48 h. [2] |
體內(nèi)活性 | The administration of Salvianolic acid B (10 mg/kg) significantly ameliorates the memory impairment induced by the Aβ25-35 peptide in the passive avoidance task (P<0.05). Additionally, Salvianolic acid B treatment reduces the number of activated microglia and astrocytes observed during the inflammatory reaction following the administration of the Aβ25-35 peptide. Furthermore, Salvianolic acid B markedly reduces the expression levels of inducible nitric oxide synthase and cyclooxygenase-2, as well as thiobarbituric acid reactive substances, which are increased by the administration of the Aβ25-35 peptide. Moreover, Salvianolic acid B administration significantly rescues the Aβ25-35 peptide-induced decrease in choline acetyltransferase and brain-derived neurotrophic factor protein levels[2]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | Saline : 25 mg/mL (34.79 mM) DMSO : 50 mg/mL (69.58 mM) |
關(guān)鍵字 | Salvianolic acid B | 115939-25-8 | Inhibitor | inhibit | Autophagy |
相關(guān)產(chǎn)品 | Hydroxychloroquine | Guanidine hydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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