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Postion:Product Catalog >SAFit2
SAFit2
  • SAFit2

SAFit2 NEW

Price $80 $197 $297
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: SAFit2 CAS No.: 1643125-33-0
Purity: 99.96% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameSAFit2
DescriptionSAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51) with a Ki value of 6 nM. SAFit2 can enhance the binding of AKT2-AS160 and participate in the downstream response of glucocorticoid release in vivo. It is a candidate compound for the treatment of obesity, chronic pain, depression and anxiety.
In vitroMETHODS: The effects of SAFit2 (1, 5, 10 μM) on macrophage migration were evaluated in a Transwell assay. RESULTS SAFit2 significantly reduced macrophage migration in a concentration-dependent manner. [4]
In vivoMETHODS: SAFit2 (20 mg/kg, intraperitoneal injection, twice a day, 10 days) was administered to mice and glucose tolerance was observed. RESULTS SAFit2 treatment significantly improved glucose tolerance. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (112.1 mM), Sonication is recommended.
KeywordsSAFit2 | SAFit-2
Inhibitors RelatedFKBP51F67V-selective antagonist Ligand2

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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