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Postion:Product Catalog >S55746
S55746
  • S55746

S55746 NEW

Price $51 $74 $110
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-13

Product Details

Product Name: S55746 CAS No.: 1448584-12-0
Purity: 97.14% Supply Ability: 10g
Release date: 2024/11/13

Product Introduction

Bioactivity

名稱S55746
描述S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).
體外活性S55746 selectively causes apoptosis through BCL-2 inhibition in a BAX/BAK-dependent manner. S55746 (0-1 μM) effectively and selectively induces cell death [1].
體內活性S55746 is a potent and well-tolerated oral BCL-2 inhibitor, effective even at doses up to 300 mg/kg. At doses of 20-100 mg/kg (p.o.), S55746 inhibits xenograft growth in RS4 [1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 44 mg/mL (61.9 mM), Sonication is recommended.
關鍵字inhibit | S-55746 | BCL-201 | Inhibitor | S 55746 | Bcl-2 Family | BCL 201 | S55746 | BLC-201 | BCL201 | BLC 201
相關產品Gossypol (acetic acid) | (S)-(+)-Ibuprofen | Allethrin | Navitoclax | Docetaxel trihydrate | Gossypol | Triacetylresveratrol | Diphenyl disulfide | Lisaftoclax | Venetoclax | (E)-Ferulic acid | Thymoquinone
相關庫高選擇性抑制劑庫 | 經典已知活性庫 | ReFRAME 相關化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2024-10-28
$51.00/1mg
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TargetMol Chemicals Inc.
2024-11-13
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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