Product Details
| Product Name:
Robinetin |
CAS No.:
490-31-3 |
| Purity:
99.61% |
Supply Ability:
10g |
| Release date:
2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Robinetin |
| 描述 | Robinetin (3,3',4',5',7-Pentahydroxyflavone) exhibits potent antioxidant and antiradical activities, effectively inhibiting EYPC membrane lipid peroxidation and HbA glycosylation. |
| 體外活性 | Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus[2]. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore[3]. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner[4]. |
| 體內(nèi)活性 | Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA[2]. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene[2] |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL (330.86 mM)
|
| 關(guān)鍵字 | Inhibitor | antibacterial | antioxidant | flavonoid | Robinetin | Bacterial | antiviral | peroxidation | antifungal | protein | inhibit | lipid | HIV Integrase | Fungal | glycosylation | antimutagenesis |
| 相關(guān)產(chǎn)品 | Neomycin sulfate | Stavudine | Dehydroacetic acid sodium | Emtricitabine | Ampicillin sodium | Dextran sulfate sodium salt (MW 4500-5500) | Kanamycin sulfate | Sulfamethoxazole sodium | Lamivudine | Doxycycline | Valproic Acid | Dimethyl sulfoxide |
| 相關(guān)庫 | 黃酮類天然產(chǎn)物庫 | 中藥單體化合物庫 | 經(jīng)典已知活性庫 | 抗真菌庫 | 天然產(chǎn)物庫 | 抗病毒庫 | 高通量篩選天然產(chǎn)物庫 | 抗衰老化合物庫 | 抗感染天然產(chǎn)物庫 | 抗病毒中藥單體化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
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Suppliers |
Update time |
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$1.00/1kg |
VIP7Y
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Career Henan Chemical Co
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2018-12-25 |
United States