Product Details
Product Name:
RO8191 |
CAS No.:
691868-88-9 |
Purity:
≥98% |
Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
名稱 | RO8191 |
描述 | RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor. |
體外活性 | RO8191 strongly suppresses HCV replicon activity at 72 h in a dose-dependent manner. RO8191 reduces levels of the proteins HCV NS3 and NS4A, which are localized mainly in the perinuclear region of the replicon cells[1]. |
體內(nèi)活性 | RO8191 significantly induces antiviral genes Oas1b, Mx1, and Pkr in the livers of six-week-old C57BL/6J mice[1]. |
存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 3 mg/mL (8.04 mM), Sonication and heating to 60℃ are recommended.
|
關(guān)鍵字 | HCV | Inhibitor | JAK | Hepatitis C virus | Interferon-alpha/beta receptor | RO-8191 | Janus kinase | EMCV | Tyk2 | HBV | interferon | RO 8191 | orally | IFNAR | RO8191 | ISGs | cccDNA | IFNAR1 | RO-4948191 | STAT | inhibit | JAK1 | CDM 3008 | Hepatitis B virus | IFNAR2 | imidazonaphthyridine | Interferon-α/β receptor | RO 4948191 | replicon | CDM3008 |
相關(guān)產(chǎn)品 | EIDD-1931 | Ribavirin | Cetylpyridinium Chloride | Nifuroxazide | Balsalazide sodium hydrate | Tenofovir Disoproxil Fumarate | Artemisinin | Niclosamide | Ruxolitinib phosphate | Diosgenin | 4-Hydroxyacetophenone | Tenofovir |
相關(guān)庫(kù) | 細(xì)胞重編程化合物庫(kù) | 抗胰腺癌化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 表觀遺傳庫(kù) | 激酶抑制劑庫(kù) | 抗病毒庫(kù) | 干細(xì)胞分化化合物庫(kù) | 已知活性化合物庫(kù) | 抗感染化合物庫(kù) | 抗肝癌化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |