Ro 363 hydrochloride NEW
| Price | $996 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Ro 363 hydrochloride | CAS No.: 250580-70-2 |
| Supply Ability: 10g | Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Ro 363 hydrochloride |
| Description | Ro 363 hydrochloride is an effective, highly selective agonist of β 1-adrenoceptor. Ro 363 hydrochloride is an effective inotropic stimulant. Ro 363 hydrochloride is a cardiovascular regulator, which can reduce diastolic blood pressure and significantly increase myocardial contractility. |
| In vitro | In isolated heart preparations from guinea-pigs, the compound Ro 363 induced arrhythmic contractions when administered at doses that elicited 70-100% of its maximal heart rate-increasing effects [1]. Additionally, in tracheal tissues of guinea-pigs that contract spontaneously, Ro 363 acted as a potent full agonist, demonstrating approximately half the effectiveness of (-)-Isoprenaline. This activity of Ro 363 is attributed to its activation of β1-receptors, as evidenced by its comparable potency to (-)-Isoprenaline in affecting the trachea, heart, and ileum [2]. |
| In vivo | In chloralose-anesthetized felines, Ro 363 exhibits negligible arrhythmogenic activity compared to epinephrine (adrenaline), especially in subjects whose cardiac sensitization has been induced by either U-0882 or halothane [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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