Rivastigmine NEW
| Price | $47 | $55 | $81 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: Rivastigmine | CAS No.: 123441-03-2 |
| Purity: 99.85% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | Rivastigmine |
| 描述 | Rivastigmine (Exelon) is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease. |
| 細胞實驗 | Chronic toxicity is assessed 7 days after continuous exposure of cells to donepezil or rivastigmine using cell viability and cell esterase activity and the estimated cell numbers as parameters for viability. Culture medium including the tested drugs is changed once after 4 days.(Only for Reference) |
| 體內活性 | Preclinical biochemical studies indicates that rivastigmine has central nervous system selectivity over peripheral inhibition. It ameliorates memory impairment in rats with forebrain lesions. The drug is rapidly absorbed orally, with a bioavailability of 0.355 and low protein binding (40%). Its elimination halflife is less than 2 hours, and it is converted to an inactive metabolite at the site of action, bypassing hepatic metabolic pathways. Its disposition essentially is unaltered in patients with renal or hepatic impairment. It also has dosedependent effects on AChE inhibition[1]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 70 mg/mL (279.62 mM), Sonication is recommended. |
| 關鍵字 | parasympathomimetic | Parkinson's | acetylcholinesteras | Alzheimer's | BBB | disease | ChE | SDZ-ENA713 | Cholinesterase (ChE) | butyrylcholinesterase | orally | cholinesterase | BChE | Inhibitor | SDZ-ENA-713 | cholinergic | inhibit | Rivastigmine |
| 相關產品 | 1-Naphthyl acetate | DL-Menthol | Ethyl (triphenylphosphoranylidene) acetate | 4-Methylbenzylidene camphor | Isoeugenol acetate | Diethyltoluamide | Nizatidine | Methyl tridecanoate | Trimethylammonium chloride | Trimyristin |
| 相關庫 | 神經(jīng)退行性疾病化合物庫 | 經(jīng)典已知活性庫 | ReFRAME 相關化合物庫 | 肝臟毒性化合物庫 | EMA 上市藥物庫 | 藥物功能重定位化合物庫 | 藥物片段庫 | 抑制劑庫 | FDA 上市藥物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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