Rifampicin NEW
| Price | $45 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Rifampicin | CAS No.: 13292-46-1 |
| Purity: 98.05% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Rifampicin |
| Description | Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses. |
| In vitro | METHODS: PC12 cells were treated with Rifampicin (25-100 μM) for 3-24 h. The expression levels of target proteins were detected by Western Blot. RESULTS: At 6 h of incubation, Rifampicin induced a significant increase in GRP78 protein expression in PC12 cells. Prolonged incubation with Rifampicin further enhanced the induction of GRP78 up to 24 h. PC12 cells showed a dose-dependent induction of GRP78 when incubated with Rifampicin at concentrations in the 25-100 μM range. [1] METHODS: Human colon cancer cells LS180 were treated with Rifampicin (10 μM) for 24-144 h. Gene levels were measured by RT-PCR. RESULTS: The total expression of NR1I2 mRNA was reduced by 40% after 24 h of Rifampicin treatment, and the expression of PXR.3 mRNA was reduced by 45% after 24 h of Rifampicin treatment. [2] |
| In vivo | Rifampicin (200, 400 mg/kg) can induce fatty liver at high concentrations [4]. Rifampicin (30?mg/kg, i.p.) treatment of S464P biofilms in vivo causes a slight decline in bioluminescence from these catheters compared with the parental signal, but it does not affect bioluminescence in mice infected with mutant H481Y [5]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (60.76 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Bacterial | Inhibitor | Rifampicin | Influenza Virus | inhibit | Orthopoxvirus | Antibiotic |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Anti-Viral Compound Library | Natural Product Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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