Product Name:    Ribavirin

Synonyms:    REBETOL;RIBAVIRIN;rtca;tribavirin;vilona;VIRAMID;VIRAZID;VIRAZOLE

CAS:    36791-04-5

MF:    C8H12N4O5

MW:    244.21

EINECS:    636-825-3

Product Categories:    Antiviral;Bases & Related Reagents;Antivirals for Research and Experimental Use;Biochemistry;Carbohydrates & Derivatives;Nucleotides;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Inhibitors;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Active Pharmaceutical Ingredients;API's;36791-04-5

Ribavirin is a clinically useful antiviral medication for Hepatitis C, viral hemorrhagic fevers and other RNA and DNA viruses. The exact mechanism of its antiviral activity is uncertain. Various proposals include inhibition of viral polymerase1, RNA mutagenesis2, and inosine monophosphate dehydrogenase (IMPDH) inhibition3. Sensitizes tumor cells to anticancer agents 5-fluorouracil5 and doxorubicin6 via inhibition of eIF4E. Displays efficacy against atypical teratoid/rhabdoid tumors7 and inhibits glioma cell growth8.