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Postion:Product Catalog >Rapanone
Rapanone
  • Rapanone

Rapanone NEW

Price $51 $113 $166
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Rapanone CAS No.: 573-40-0
Purity: 99.72% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameRapanone
DescriptionRapanone (2,5-Dihydroxy-3-tridecyl-[1,4]benzoquinone) is a natural benzoquinone that is a potent and selective inhibitor of human synovial PLA2.
In vitroIn the HepG2, rapanone (20–40 μM) induced a concentration-dependent mitochondrial membrane potential dissipation, ATP depletion, hydrogen peroxide generation and, phosphatidyl serine externalization.Rapanone impairs mitochondrial respiration by inhibiting electron transport chain at Complex III and promotes mitochondrial dysfunction[1].
In vivoIn mice,rapanone (2.5-10 mg/kg; i.p.) exhibits anti-inflammatory effects in the carrageenan paw oedema model
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 65 mg/ml (201.59 mM)
KeywordsRapanone | antioxidant | anti-inflammatory | Bacterial | inhibit | anti-tumor | Phospholipase | antiparasiti | synovial | PLA2 | Parasite | benzoquinone | antibacterial | Apoptosis | Inhibitor
Inhibitors RelatedNeomycin sulfate | Stavudine | Ampicillin sodium | Kojic acid | Dextran sulfate sodium salt (MW 4500-5500) | Kanamycin sulfate | Sulfamethoxazole sodium | Hydroxychloroquine | Doxycycline | Tributyrin | Dimethyl sulfoxide | Oleic acid
Related Compound LibrariesAnti-Tumor Natural Product Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Inhibitor Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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