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![(R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride](/ProductImageEN/2024-04/Small/ea59c228-5907-4fb6-8c1c-b5aa06788427.gif)
(R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride NEW
| Price | $8 | $7 | $6 |
| Package | 1kg | 100kg | 1000kg |
| Min. Order: | 1kg |
| Supply Ability: | g-kg-tons, free sample is available |
| Update Time: | 2024-04-23 |
Product Details
| Product Name: (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride | CAS No.: 86347-15-1 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2024/04/23 |
| Lead time: In stock | Packaging: bottle/drum/bucket/IBC, as request. |
| Delivery: By sea, by air, by express | Origin: Manufacturer |
| Contact person: Jessica |
1. Product information
| Name | (R)-4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Medetomidine Hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties.Target: Adrenergic alpha-2 ReceptorMedetomidine, acting at alpha(2A) adrenoceptors, must be present during the encoding process to decrease discrete cue fear memory; however, its ability to suppress contextual memory is likely the result of blocking the consolidation process [1]. Medetomidine had no analgesic effects in alpha(2A)-adrenoceptor KO mice [2]. Medetomidine was effective in blocking these sympathomimetic actions of cocaine even in all 7 subjects who were homozygous for the Del322-325 polymorphism in the alpha2C AR, a loss-of-function mutation that is highly enriched in blacks [3]. |
|---|---|
| Related Catalog | Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease |
| References | [1]. Davies, M.F., et al., Activation of alpha2 adrenergic receptors suppresses fear conditioning: expression of c-Fos and phosphorylated CREB in mouse amygdala. Neuropsychopharmacology, 2004. 29(2): p. 229-39. [2]. Ozdogan, U.K., et al., The involvement of alpha 2A-adrenoceptors in morphine analgesia, tolerance and withdrawal in mice. Eur J Pharmacol, 2004. 497(2): p. 161-71. [3]. Menon, D.V., et al., Central sympatholysis as a novel countermeasure for cocaine-induced sympathetic activation and vasoconstriction in humans. J Am Coll Cardiol, 2007. 50(7): p. 626-33. |
| Boiling Point | 381.9oC at 760 mmHg |
|---|---|
| Melting Point | 164-166°C |
| Molecular Formula | C13H17ClN2 |
| Molecular Weight | 236.740 |
| Flash Point | 191.3oC |
| Exact Mass | 236.108032 |
| PSA | 28.68000 |
| LogP | 3.98030 |
| Storage condition | Refrigerator |
| HS Code | 2942000000 |
|---|
2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Mob: 86 17630971917
WhatsApp/Skype/Wechat/LINE: 86 17630971917
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China
- Since: 2023-02-10
- Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro