Puromycin dihydrochloride NEW
| Price | $39 | $70 | $122 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-30 |
Product Details
| Product Name: Puromycin dihydrochloride | CAS No.: 58-58-2 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2025/04/30 |
Product Introduction
Bioactivity
| Name | Puromycin dihydrochloride |
| Description | Puromycin dihydrochloride (CL13900 dihydrochloride) is a cinnamamide adenosine antibiotic and an inhibitor of protein synthesis. Puromycin dihydrochloride inhibits protein synthesis by binding to RNA and has antitumor and antitrypanosomal activity. |
| In vitro | METHODS: Human hepatocellular carcinoma cells, HepG2, and primary rat hepatocytes, PRH, were treated with Puromycin dihydrochloride (0-300 μmol/L) for 72 h, and cell growth inhibition was detected by MTT. RESULTS: Puromycin dihydrochloride dose-dependently inhibited the growth of HepG2 and PRH cells, with IC50s of 1600 μmol/L and 2000 nmol/L, respectively.[1] METHODS: Human breast cancer cells MDA-MB-231 and MDA-MB-436 were transfected with shRNAs-Puro lentivirus, and after 24 h, the transfected cells were cultured in new medium containing Puromycin dihydrochloride (1 μg/ml) for about 12 days, and then the cells were screened for the success of transfection. RESULTS: Puromycin dihydrochloride screened the lentivirally transfected cells successfully. [2] METHODS: Cells transfected with lentivirus were cultured in medium supplemented with Puromycin dihydrochloride (2 μg/mL). RESULTS: Puromycin dihydrochloride screened and maintained lentivirally successfully transfected cells. [3] |
| In vivo | Puromycin is utilized to select recombinant cells from non-cultured cells. It serves as a tool for studying protein synthesis in many systems. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 92 mg/mL (168.98 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 60 mg/mL (110.2 mM), Sonication is recommended. |
| Keywords | RNASynthesis | RNA Synthesis | Puromycin dihydrochloride | Puromycin Dihydrochloride | Puromycin | Inhibitor | inhibit | DNASynthesis | DNA synthesis | DNA Synthesis | CL-13900 Dihydrochloride | CL13900 Dihydrochloride | CL-13900 | CL13900 | CL 13900 Dihydrochloride | CL 13900 | Bacterial | Antibiotic | 60S ribosome |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | Urethane | Sulfamethoxazole sodium | Guanidine hydrochloride | Doxycycline | Thymidine | Isoeugenol | Dimethyl sulfoxide |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Anti-Parasitic Compound Library | Bioactive Compound Library | Natural Product Library | Microbial Natural Product Library | Inhibitor Library | Antiparasitic Natural Product Library | Natural Product Library for HTS | Anti-Aging Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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