PSI-697 NEW
| Price | $1820 | $2380 | $3100 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-13 |
Product Details
| Product Name: PSI-697 | CAS No.: 851546-61-7 |
| Supply Ability: 10g | Release date: 2024/11/13 |
Product Introduction
Bioactivity
| 名稱 | PSI-697 |
| 描述 | PSI-697 is an inhibitor of oral P-selectin (IC50: 125 μM). |
| 體外活性 | PSI-697 inhibits the binding of a soluble human P-selectin to PSGL-1. In vitro, as a reproducible concentration-dependent manner inhibiting 50% of binding at a concentration of 125 μM [1]. |
| 體內(nèi)活性 | PSI-697 (30 mg/kg; p.o.; daily; 6 days) promotes thrombus resolution and reduces inflammation in a baboon model of venous thrombosis. PSI-697 ((30 mg/kg; i.g.; daily) decreases vein wall injury in a rat stenosis model of venous thrombosis. PSI-697 (100 mg/kg; p.o.) reduces thrombus weight by 18% relative to the vehicle, without prolonging bleeding time in a rat venous thrombosis model. PSI-697 (0-50 mg/kg; p.o.) obviously decreases the number of rolling leukocytes by 39% versus vehicle control[1][2]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 45.8 mg/mL (124.51 mM) |
| 關(guān)鍵字 | PSI-697 | PSI 697 | PSI697 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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