Procyanidin B2 NEW
| Price | $146 | $350 |
| Package | 5mg | 20mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Procyanidin B2 | CAS No.: 29106-49-8 |
| Purity: 99.21% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱 | Procyanidin B2 |
| 描述 | Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. |
| 動物實驗 | Streptozotocin-induced diabetic rats were fed with either 3% cinnamon or 0.002% Procyanidin B2(PCB2)-fraction in diet for 12weeks. Biochemical analysis of blood and urine was performed at the end of experiment. Evaluation of glomerular markers that serve as indicators of renal function was done by immunohistochemistry, immunoblotting and qRT-PCR. Supplementation of diabetic rats with cinnamon and PCB2-fraction prevented glycation mediated RBC-IgG cross-links and HbA1c accumulation in diabetes rats. Cinnamon and PCB2-fraction also inhibited the accumulation of N-carboxy methyl lysine (CML), a prominent AGE in diabetic kidney[2]. |
| 體外活性 | Procyanidin B2 exerts both antioxidant and pro-oxidant properties by interacting with H2O2 and metal ions[1]. |
| 體內活性 | Procyanidin B2 from cinnamon inhibited AGE accumulation in diabetic rat kidney and ameliorated AGE mediated pathogenesis of DN[2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (86.43 mM) |
| 關鍵字 | inhibit | Proanthocyanidin B 2 | Procyanidin B 2 | Inhibitor | Proanthocyanidin B-2 | Reactive Oxygen Species | Procyanidin B2 | Procyanidin B-2 |
| 相關產品 | Sodium Thiocyanate | Imeglimin hydrochloride | L-Ascorbic acid | α-Vitamin E | Ammonium sulfate | Glucosamine | D-(+)-Glucono-1,5-lactone | Tempol | Lycopene | Coenzyme Q10 | 3-Amino-1,2,4-triazole | Naringenin |
| 相關庫 | 抗癌天然產物庫 | 黃酮類天然產物庫 | 經典已知活性庫 | 中藥單體化合物庫 | 天然產物庫 | 已知活性化合物庫 | 古代經典名方目錄分子庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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