Product Details
| Product Name:
Pluripotin |
CAS No.:
839707-37-8 |
| Purity:
98.82% |
Supply Ability:
10g |
| Release date:
2024/11/14 |
Product Introduction
Bioactivity
| 名稱(chēng) | Pluripotin |
| 描述 | Pluripotin (SC1) (SC1), which keep embryonic stem cell (ESC) self-renewal, is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. |
| 體外活性 | Pluripotin is a dual function small molecule inhibitor of both ERK1 and RasGAP and that simultaneous inhibition of both protein activities is required and sufficient for Pluripotin's effects on mES cells. Pluripotin activates Ras by inhibition of RasGAP function[1]. Pluripotin improved the derivation efficiency and pluripotency of ES cells from C57BL/6. Three types of pluripotent stem cells (fES, ntES, and iPS cells) of the C57BL/6 background could generate full-term pups with high efficiency when cultured with Pluripotin[1]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 13.8 mg/mL (25 mM)
|
| 關(guān)鍵字 | inhibit | Extracellular signal regulated kinases | Ribosomal S6 Kinase (RSK) | Inhibitor | SC-1 | ERK | Pluripotin | S6K | SC 1 |
| 相關(guān)產(chǎn)品 | TBHQ | Notoginsenoside R1 | Regorafenib monohydrate | Lidocaine | Sorafenib | Astragaloside IV | Lidocaine hydrochloride | Regorafenib | Dabrafenib | Sorafenib tosylate | Tauroursodeoxycholate | Sodium salicylate |
| 相關(guān)庫(kù) | 疼痛相關(guān)化合物庫(kù) | 經(jīng)典已知活性庫(kù) | 激酶抑制劑庫(kù) | 抗癌臨床化合物庫(kù) | 藥物功能重定位化合物庫(kù) | 抑制劑庫(kù) | 抗衰老化合物庫(kù) | 已知活性化合物庫(kù) | 抗癌藥物庫(kù) | 抗癌活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1.00/1KG |
VIP5Y
|
Career Henan Chemical Co
|
2020-03-11 |
United States