Pitavastatin calcium NEW
| Price | $34 | $54 | $76 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Pitavastatin calcium | CAS No.: 147526-32-7 |
| Purity: 99.49% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Pitavastatin calcium |
| Description | Pitavastatin calcium (NK-104) is a potent inhibitor of HMG-CoA reductase (Ki: 1.7 nM). It lowers both total cholesterol and low-density lipoprotein cholesterol in animals and humans. Metabolism of pitavastatin by the cytochrome P450 system is minimal, reducing the risk of drug-drug interactions. |
| In vivo | Pitavastatin inhibits the progression of arterial atherosclerosis by blocking the synthesis of thromboxane and suppressing the migration or proliferation of vascular smooth muscle induced by angiotensin II, thereby stabilizing atherosclerotic plaques. It significantly reduces the levels of intracellular and synthesized cholesteryl esters. Moreover, pitavastatin enhances the extracellular expression of LDL receptors and increases the binding of LDL to LDL receptors. Compared to simvastatin and atorvastatin, pitavastatin is more effective in inducing the expression of LDL receptor mRNA. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (56.75 mM) |
| Keywords | Pitavastatin calcium | NK104 | Apoptosis | HMG-CoA Reductase (HMGCR) | P 872441 | inhibit | Pitavastatin | P872441 | Inhibitor | NK 104 | Mitophagy | Autophagy | NK-104 hemicalcium | Mitochondrial Autophagy |
| Inhibitors Related | Sucrose | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Tributyrin | Ferulic Acid | Paeonol | Glycerol | Thymidine |
| Related Compound Libraries | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | Neuroprotective Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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