Pirfenidone NEW
Price | Get Latest Price |
Package | 25kg |
Min. Order: | 1kg |
Supply Ability: | 20ton |
Update Time: | 2023-07-27 |
Product Details
Product Name: Pirfenidone | CAS No.: 53179-13-8 |
EC-No.: 621-260-7 | Min. Order: 1kg |
Purity: 99% | Supply Ability: 20ton |
Release date: 2023/07/27 |
Product Name: | Pirfenidone |
Synonyms: | 5-Methyl-1-phenylpyridine-2(1H)-one;S-7701;5-methyl-1-phenyl-2-pyridone;5-methyl-1-phenyl-pyridin-2-one;5-methyl-1-phenylpyridin-2-one;Pirfenidone, >=99%;5-methyl-1-phenylpyridin-2(1H)-one;Pirfenidone(S-7701,AMR-69) |
CAS: | 53179-13-8 |
MF: | C12H11NO |
MW: | 185.22 |
EINECS: | 621-260-7 |
Product Categories: | Cytokine signaling;Inhibitors;Aromatics Compounds;Aromatics;Smad;TGF-beta;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;53179-13-8 |
Mol File: | 53179-13-8.mol |
Melting point | 96-97°C |
Boiling point | 329.1±15.0 °C(Predicted) |
density | 1.137±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
solubility | DMSO: ≥10 mg/mL, soluble |
form | solid |
pka | -0.16±0.63(Predicted) |
color | Off-white |
Water Solubility | Soluble to 20 mM in water |
Stability: | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month. |
InChIKey | ISWRGOKTTBVCFA-UHFFFAOYSA-N |
CAS DataBase Reference | 53179-13-8(CAS DataBase Reference) |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 36-24/25 |
WGK Germany | 3 |
RTECS | UV1148200 |
HS Code | 29337900 |
Hazardous Substances Data | 53179-13-8(Hazardous Substances Data) |
Uses | Pirfenidone is a broad-spectrum antifibrotic drug that modulates diverse cytokine action involving TGF-β, TNF-α, epidermal growth factor, platelet-derived growth factor,vascular endothelial growth factor, insulin-like growth factor 1, fibroblast growth factor, and others.Pirfenidone has been effective in the prevention and regression of pulmonary fibrosis, peritoneal sclerosis, hepatic cirrhosis, uterine fibromyoma, and other scarring and fibrotic conditions. It doesn’t cure the condition or reverse any existing scarring but it can effectively slow down the rate of lung function decline by about 50%. In the UK, Pirfenidone is currently only approved for treating IPF, and not for other forms of pulmonary fibrosis. |
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- Since: 2017-12-08
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