Pim-1/2 kinase inhibitor 1 NEW
Price | $34 | $77 | $127 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Pim-1/2 kinase inhibitor 1 | CAS No.: 6320-51-0 |
Purity: 99.89% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Pim-1/2 kinase inhibitor 1 |
描述 | Pim-1/2 Kinase Inhibitor 1, an orally active inhibitor, impedes the action of Pim kinases by preventing their ability to phosphorylate peptides. It particularly inhibits the phosphorylation of 4E-BP1 and p27 Kip1 by Pim protein kinases. This compound is valuable in cancer research, with a notable application in studying prostate cancer [1]. |
體外活性 | Pim-1/2 kinase inhibitor 1 (compound D14) exhibits cytotoxicity to PC3 cells, with an IC of 11 μM after 48 hours of incubation at varying concentrations [1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (212.53 mM), Sonication and heating to 60℃ are recommended. |
關(guān)鍵字 | Pim-1/2 kinase inhibitor 1 | 2,4 Thiazolidinedione, 5 p methoxybenzylidene | 2,4Thiazolidinedione, 5pmethoxybenzylidene |
相關(guān)產(chǎn)品 | XL413 hydrochloride | HJ-PI01 | SGI-1776 | CK2/ERK8-IN-1 | M-110 | (Z)-SMI-4a | XL413 HCl | CX-6258 hydrochloride | Pim-1 kinase inhibitor 4 | Pim-1 kinase inhibitor 8 | TP-3654 | K00135 |
相關(guān)庫 | 抗肺癌化合物庫 | 抗胰腺癌化合物庫 | 經(jīng)典已知活性庫 | 表觀遺傳庫 | 激酶抑制劑庫 | 抑制劑庫 | 已知活性化合物庫 | 抗癌化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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