PEG400 NEW
| Price | $46 |
| Package | 100mL |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: PEG400 | Purity: 98% |
| Supply Ability: 10g | Release date: 2024/11/18 |
Product Introduction
Bioactivity
| 名稱(chēng) | PEG400 |
| 描述 | PEG400 (Polyethylene glycol 400) is a polymer formed from repeating units of ethylene glycol that is water soluble, low immunogenicity, and biocompatible. PEG400 is a neutral polymer with a molecular weight of 400. |
| 體外活性 | METHODS: Human colorectal adenocarcinoma cells Caco-2 were treated with PEG400 (30 w/v% in 100 μL) for 30 min, and cell growth inhibition was detected by MTT. RESULTS: PEG400 treatment reduced cell viability, which was 42%±2% compared with the control. [1] |
| 體內(nèi)活性 | METHODS: To study in vivo activity, Simvastatin (60 mg/kg, aqueous 2% DMSO+30% PEG 400+5% Tween 80) was administered by gavage to C57BL/6J mice once daily for six weeks on a CF diet. RESULTS: Simvastatin treatment reduced serum cholesterol levels by 18%, and retinal cholesterol and lipoprotein cholesterol levels by 24% and 21%, respectively. [2] METHODS: To study the effect of Rapamycin on life expectancy, Rapamycin (8 mg/kg in DMSO+5% PEG-400+5% Tween-80) was administered intraperitoneally to 20-21 month old C57BL/6J mice once daily for three months. RESULTS: Three months of Rapamycin treatment was sufficient to increase the life expectancy of middle-aged mice by 60% and improve their healthy lifespan. [3] |
| 存儲(chǔ)條件 | store at 4°C | Shipping with blue ice. |
| 溶解度 | DMSO : 100 mg/mL, Sonication is recommended. H2O : 100 mg/mL, Sonication is recommended. |
| 關(guān)鍵字 | PEG 400 | 25322-68-3 | PEG-400 | PEG400 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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