PEG300 NEW
| Price | $48 |
| Package | 100mL |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: PEG300 | CAS No.: 25322-68-3 |
| Purity: mw~300 | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | PEG300 |
| Description | PEG300 (Polyethylene glycol 300) is a polymer formed from repeating units of ethylene glycol that is water soluble, low immunogenicity, and biocompatible. PEG300 is a neutral polymer with a molecular weight of 300. |
| In vitro | METHODS: Human colorectal adenocarcinoma cells Caco-2 were treated with PEG300 (30 w/v% in 100 μL) for 30 min, and cell growth inhibition was detected by MTT. RESULTS: PEG300 treatment severely reduced cell viability, and the cell survival rate was only 20%. [1] |
| In vivo | METHODS: To study the effect of Dasatinib on diabetic cardiomyopathy, Dasatinib (5 mg/kg in 10% DMSO + 90% PEG-300) was administered by gavage to BKS.Cg-+Leprdb/+Leprdb/OlaHsd (db/db) mice once a week for four weeks. RESULTS: Dasatinib counteracted obesity in the heart and bone marrow as well as cardiac fibrosis. [2] METHODS: To test the in vivo effects of treatment with ALW-II-41-27 (an EPHA2 inhibitor) and/or cetuximab, cetuximab (25 mg/kg in 10% 1-methyl-2-pyrrolidinone + 90% PEG 300 twice weekly) and ALW-II-41-27 (30 mg/kg/day) were injected intraperitoneally into balb/c athymic (nu+/nu+) mice bearing human colorectal adenocarcinoma tumor HCT15 for six weeks. RESULTS: The combination of ALW-II-41-27 and cetuximab significantly inhibited tumor growth. [3] |
| Storage | store at 4°C | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (333.33 mM), Sonication is recommended. H2O : 50 mg/mL (166.67 mM) |
| Keywords | immunogenic | Polyethylene glycol300 | biocompatible | PEG 300 | marker | PEG300 | gastrointestinal | inhibit | polymer | PEG-300 | Inhibitor | Polyethylene glycol-300 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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