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Postion:Product Catalog >PACMA 31
PACMA 31
  • PACMA 31

PACMA 31 NEW

Price $41 $59 $97
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: PACMA 31 CAS No.: 1401089-31-3
Purity: 99.79% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱PACMA 31
描述PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 μM. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.
體外活性In OVCAR-8 cells, PACMA 31 (0-10 μM) potently inhibits colony formation in a dose-dependent manner[1].
體內活性In human ovarian cancer mouse xenografts, PACMA 31 (20-200 mg/kg) i.p. or per os administration of significantly inhibited tumor growth by 85% and 65% at day 62, respectively[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (232.3 mM), Sonication is recommended.
關鍵字bond | tumor | PACMA31 | ovarian | athymic | inhibit | toxicity | colony | mice | oral | PACMA-31 | Inhibitor | covalent | PACMA 31
相關庫經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 | 共價抑制劑庫 | 抗癌化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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