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Postion:Product Catalog >PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)
PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)
  • PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)

PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc) NEW

Price $600
Package 50μg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc) Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

NamePACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)
DescriptionPituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors (?Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and downstream signaling cascades. Studies point to the potential role of the (pituitary) adenylate cyclase activating polypeptide receptor 1 (ADCYAP1R1) gene, which has been implicated in stress response, in posttraumatic stress disorder (PTSD). Pituitary adenylate cyclase-activating polypeptide (PACAP; Adcyap1) and its cognate PAC1 receptor (Adcyap1r1) are expressed in peripheral nociceptive pathways, participate in anxiety-related responses and have been have been linked to posttraumatic stress disorder and other mental health afflictions. Recent studies revealed the role of the PAC1 (ADCYAP1R1) gene variability in vulnerability to posttraumatic stress disorder in women. Due to the relatively high comorbidity of posttraumatic stress disorder and substance use disorder, we hypothesized about possible associations between PAC1 gene and problematic alcohol use.
StorageShipping with blue ice.
KeywordsPAC-1 | PAC 1

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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$386.00/100μg
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TargetMol Chemicals Inc.
2024-11-18
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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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