p-Ethynylphenylalanine hydrochloride NEW
| Price | $30 | $45 | $64 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: p-Ethynylphenylalanine hydrochloride | CAS No.: 188640-63-3 |
| Purity: 99.03% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | p-Ethynylphenylalanine hydrochloride |
| Description | p-Ethynylphenylalanine hydrochloride (4-Ethynyl-L-phenylalanine HCL) is a novel, potent, and specific inhibitor of TPH[1]. Its potential to selectively and reversibly inhibit serotonin biosynthesis may contribute to characterizing the role of serotonin in behavioral and physiological activities[1]. |
| In vitro | p-Ethynylphenylalanine hydrochloride was demonstrated to inhibit competitively and reversibly TPH in vitro (Ki = 32.6 +/- 6.2 microM vs. tryptophan)[1]. |
| In vivo | Administration of p-Ethynylphenylalanine hydrochloride (30 mg/kg) to rats produced a 95 +/- 5% decrease in TPH activity in brain homogenates and a concomitant decrease in serotonin and 5-hydroxyindole-3-acetic acid levels (85%) at 24 h after injection[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 12 mg/mL (53.17 mM), Sonication is recommended. DMSO : 99 mg/mL (438.69 mM), Sonication is recommended. |
| Keywords | p-Ethynylphenylalanine | p Ethynylphenylalanine hydrochloride | 5-HT | inhibit | 5-HIAA | Tryptophan Hydroxylase | hydroxylase | p-Ethynylphenylalanine Hydrochloride | Inhibitor | tryptophan | serotonin | TPH | pEthynylphenylalanine hydrochloride |
| Inhibitors Related | p-Ethynylphenylalanine | Mildronate | Tetrahydropapaverine hydrochloride | Casein | p-Fluoro-L-phenylalanine | Telotristat Etiprate | Ketoconazole | Bupicomide | Diethyl-pythiDC | Fenclonine | Nepicastat hydrochloride | Sapropterin dihydrochloride |
| Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Covalent Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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