Oxyfedrine NEW
| Price | $3368 | $3980 | $5500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Oxyfedrine | CAS No.: 15687-41-9 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Oxyfedrine |
| Description | Oxyfedrine is an orally active β-adrenoreceptor agonist. Oxyfedrine is a vasodilator that reduces coronary vessels tonicity that can be used in cardiovascular disease research[1] [2]. |
| In vitro | Oxyfedrine, at a concentration of 50 μM for 48 hours, reduces aldehyde dehydrogenase (ALDH) activity in HCT116 and HSC-4 cells, and functions as a sensitizer to GSH-depleting agents, consequently enhancing cell death in these cell lines when used in combination with such drugs [1]. Additionally, oxyfedrine, within a dosage range of 0-1 μg/mL, hampers spontaneous myogenic activity in the rat isolated portal vein [4]. |
| In vivo | Oxyfedrine, administered at various dosages and by different routes across multiple studies, exhibits diverse pharmacological actions. At a dosage of 14 mg/kg through oral administration (p.o.) for 3-4 weeks in cats, oxyfedrine demonstrates anti-anginal properties [2]. In a model utilizing HCT116 cell xenograft mice, oxyfedrine (10 mg/kg, intraperitoneally i.p.) combined with sulfasalazine (SSZ, 350 mg/kg, i.p.) effectively suppresses tumor growth [1]. Furthermore, at a lower dosage of 1 mg/kg administered intravenously (i.v.), oxyfedrine reduces both arterial and venous blood viscosity under conditions of ice water-induced stress in rats [3]. Detailed results from the cat model indicate oxyfedrine decreases systolic and diastolic blood pressures, while increasing heart rate and cardiac output [2]. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
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