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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Antifungal Drugs>Oxiconazole nitrate
Oxiconazole nitrate
  • Oxiconazole nitrate

Oxiconazole nitrate NEW

Price $35 $52 $103
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: Oxiconazole nitrate CAS No.: 64211-46-7
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱Oxiconazole nitrate
描述Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This disruption of membrane synthesis and integrity alters permeability, promotes loss of essential intracellular components, and inhibits fungal cell growth.
體內(nèi)活性Fusidin(Fusidate Sodium) ameliorates EAM, at least partly, through an inhibitory action on the secretion of TNF-a[1]. It markedly attenuates clinical and histological signs of immunoinflammatory diabetes mellitus in mice given streptozotocin(SZ). The effect is dose-dependent, observed in three different strains of mice. Thus, fusidin might have an antidiabetogenic effect[2].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 50 mg/mL (101.6 mM)
關(guān)鍵字HCT116 | Fungal | CYPs | Cytochrome P450 | PRDX2 | Antifungal | CYP3A4 | Inhibitor | Oxiconazole Nitrate | BALB/c nude mice | Oxiconazole nitrate | Oxiconazole | inhibit | colorectal cancer | Rifampicin
相關(guān)產(chǎn)品Neomycin sulfate | Sulfamethoxazole sodium | Doxycycline
相關(guān)庫經(jīng)典已知活性庫 | 抗真菌庫 | 藥物功能重定位化合物庫 | 抗癌上市藥物庫 | 已知活性化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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