Oxiconazole nitrate NEW
Price | $35 | $52 | $103 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Oxiconazole nitrate | CAS No.: 64211-46-7 |
Purity: 99.66% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Oxiconazole nitrate |
描述 | Oxiconazole nitrate (Ro 13-8996) is the nitrate salt form of oxiconazole, a broad-spectrum imidazole derivative with antifungal activity. Likely inhibiting cytochrome P450-dependent demethylation of lanosterol, it prevents ergosterol synthesis, a crucial component of the fungal cell membrane. This disruption of membrane synthesis and integrity alters permeability, promotes loss of essential intracellular components, and inhibits fungal cell growth. |
體內(nèi)活性 | Fusidin(Fusidate Sodium) ameliorates EAM, at least partly, through an inhibitory action on the secretion of TNF-a[1]. It markedly attenuates clinical and histological signs of immunoinflammatory diabetes mellitus in mice given streptozotocin(SZ). The effect is dose-dependent, observed in three different strains of mice. Thus, fusidin might have an antidiabetogenic effect[2]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 50 mg/mL (101.6 mM) |
關(guān)鍵字 | HCT116 | Fungal | CYPs | Cytochrome P450 | PRDX2 | Antifungal | CYP3A4 | Inhibitor | Oxiconazole Nitrate | BALB/c nude mice | Oxiconazole nitrate | Oxiconazole | inhibit | colorectal cancer | Rifampicin |
相關(guān)產(chǎn)品 | Neomycin sulfate | Sulfamethoxazole sodium | Doxycycline |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗真菌庫 | 藥物功能重定位化合物庫 | 抗癌上市藥物庫 | 已知活性化合物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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