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Postion:Product Catalog >ORM-10921
ORM-10921
  • ORM-10921

ORM-10921 NEW

Price $397 $970 $1290
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ORM-10921 CAS No.: 610782-82-6
Purity: 99.75% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameORM-10921
DescriptionORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.
In vivoThe role of the α2C-AR in modulating two key depression-related behaviors in the Flinders Sensitive Line (FSL) rat was studied using a dose-response analysis following subcutaneous administration with the selective α2C-AR antagonist ORM-10921 (0.03, 0.3?mg/kg), the nonselective α2-AR antagonist idazoxan (3?mg/kg), or vehicle once daily for 14 days. Behavior in the novel object recognition test forced swim test (FST), and locomotor activity test was assessed. ORM-10921 at both doses but not idazoxan significantly reversed immobility in the FST as well as attenuated cognitive deficits in FSL animals.[3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 45 mg/mL (157.68 mM)
KeywordsORM-10921
Inhibitors RelatedOlanzapine | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Phenylephrine hydrochloride | Isoprenaline hydrochloride | Amitriptyline hydrochloride | Labetalol hydrochloride | Trazodone hydrochloride | Mianserin hydrochloride
Related Compound LibrariesBioactive Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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