Nystatin NEW
| Price | $39 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Nystatin | CAS No.: 1400-61-9 |
| Purity: 99.36% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Nystatin |
| Description | Nystatin (Fungicidin) is a topical and oral antifungal agent with activity against many species of yeast and candida albicans, which is used largely to treat skin and oropharyngeal candidiasis. |
| In vitro | METHODS: Hippocampal neurons were treated with Nystatin (2.5-25 μM) for 30 min and cell morphology was examined. RESULTS: Acute incubation with different concentrations of Nystatin increased the growth cone size of hippocampal neurons. [1] METHODS: CHO cells were treated with Nystatin (100-300 μmol/L) for 10-60 min, and cell viability was measured by MST-1 assay. RESULTS: Cell viability studies after Nystatin application showed significant concentration- and time-dependent effects. At Nystatin concentrations equal to 100 μmol/L, the percentage of viable cells was significantly higher compared to higher concentrations. [2] |
| In vivo | Nystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues rather than in normal tissues of tumor-bearing mice, ultimately leading to elevated antiangiogenic and antitumor efficacies of endostatin in vivo[3].?Liposomal?Nystatin, at doses as low as 2 mg/kg of body weight/day, protects neutropenic mice against Aspergillus-induced death in a statistically significant manner at the 50-day time point compared to either the no-treatment, the saline, or the empty-liposome group[4]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 50 mg/mL (53.99 mM) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (5.4 mM), Suspension. Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. |
| Keywords | Fungal | Inhibitor | Apoptosis | inhibit | Antibiotic | Nystatin |
| Inhibitors Related | Neomycin sulfate | Sulfamethoxazole sodium | Tributyrin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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