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Postion:Product Catalog >NTP42
NTP42
  • NTP42

NTP42 NEW

Price $57 $143 $226
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: NTP42 CAS No.: 2055599-51-2
Purity: 99.09% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱NTP42
描述NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
體內(nèi)活性From haemodynamic assessments, NTP42 reduced the MCT-induced PAH, including mean pulmonary arterial pressure (mPAP) and right systolic ventricular pressure (RSVP), being at least comparable to the standard-of-care drugs Sildenafil or Selexipag in bringing about these effects.?Moreover, NTP42 was superior to Sildenafil and Selexipag in significantly reducing pulmonary vascular remodelling, inflammatory mast cell infiltration and fibrosis in MCT-treated animals[1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 30 mg/mL (58.19 mM), Sonication is recommended.
關(guān)鍵字pulmonary | Inhibitor | inhibit | PAH | NTP-42 | hypertension | NTP42 | TXA2 | thromboxane | arterial | Prostaglandin Receptor | NTP 42
相關(guān)產(chǎn)品PHYTOL | Tranilast | BADGE | Daidzein | Fenofibrate | Rutin | Pioglitazone hydrochloride | 5-Aminosalicylic Acid | Naringenin | Fisetin | 2,3-Butanediol | Icariin
相關(guān)庫疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗衰老化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 | 抗癌藥物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$57.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-14
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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