NP-G2-044 NEW
Price | $48 | $68 | $101 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-07 |
Product Details
Product Name: NP-G2-044 | CAS No.: 1807454-59-6 |
Purity: 99.66% | Supply Ability: 10g |
Release date: 2024/11/07 |
Product Introduction
Bioactivity
名稱 | NP-G2-044 |
描述 | NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response. |
體外活性 | NP-G2-044 inhibits the migration of MDA-MB-231 tumor cells with an IC50 of approximately 10 μM, reducing filopodial and subsequently lamellipodial formation[1]. |
體內(nèi)活性 | NP-G2-044 (100 mg/kg; i.p.; daily for 18 days) inhibits breast tumor metastasis in mouse models[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 100 mg/mL (250.39 mM), Sonication is recommended. |
關(guān)鍵字 | inhibit | formation | filopodial | cell | NPG2044 | fascin | filaments | migration | metastasis | NP G2 044 | NP-G2-044 | actin | NP-G-2-044 | Inhibitor |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗乳腺癌化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗前列腺癌化合物庫 | 口服活性化合物庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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