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Postion:Product Catalog >NP-G2-044
NP-G2-044
  • NP-G2-044

NP-G2-044 NEW

Price $48 $68 $101
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-07

Product Details

Product Name: NP-G2-044 CAS No.: 1807454-59-6
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/07

Product Introduction

Bioactivity

名稱NP-G2-044
描述NP-G2-044 is an orally active fascin inhibitor, with an IC50 of ~2 μM. It blocks tumor metastasis and increases antitumor immune response.
體外活性NP-G2-044 inhibits the migration of MDA-MB-231 tumor cells with an IC50 of approximately 10 μM, reducing filopodial and subsequently lamellipodial formation[1].
體內(nèi)活性NP-G2-044 (100 mg/kg; i.p.; daily for 18 days) inhibits breast tumor metastasis in mouse models[1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (250.39 mM), Sonication is recommended.
關(guān)鍵字inhibit | formation | filopodial | cell | NPG2044 | fascin | filaments | migration | metastasis | NP G2 044 | NP-G2-044 | actin | NP-G-2-044 | Inhibitor
相關(guān)庫經(jīng)典已知活性庫 | 抗乳腺癌化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 抗前列腺癌化合物庫 | 口服活性化合物庫 | 已知活性化合物庫 | 抗癌藥物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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