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Postion:Product Catalog >Nolatrexed dihydrochloride
Nolatrexed dihydrochloride
  • Nolatrexed dihydrochloride

Nolatrexed dihydrochloride NEW

Price $44 $73 $147
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-29

Product Details

Product Name: Nolatrexed dihydrochloride CAS No.: 152946-68-4
Purity: 97.02% Supply Ability: 10g
Release date: 2025/04/29

Product Introduction

Bioactivity

NameNolatrexed dihydrochloride
DescriptionNolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : >10 mM, Sonication is recommended.
KeywordsThymidylate Synthase | Thymidylate synthase | RNASynthesis | RNA Synthesis | Nolatrexed Dihydrochloride | Nolatrexed dihydrochloride | Nolatrexed | Inhibitor | inhibit | DNASynthesis | DNA Synthesis | AG-337 | AG337
Inhibitors Related5-Fluorouracil | Procaine | Rifaximin | Ribavirin | Guanidine hydrochloride | Trimethoprim | N-Nitrosodiethylamine | Cytarabine | Acyclovir | Thymidine | Temozolomide | Folic acid
Related Compound LibrariesApoptosis Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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