
Nolatrexed dihydrochloride NEW
Price | $44 | $73 | $147 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-04-29 |
Product Details
Product Name: Nolatrexed dihydrochloride | CAS No.: 152946-68-4 |
Purity: 97.02% | Supply Ability: 10g |
Release date: 2025/04/29 |
Product Introduction
Bioactivity
Name | Nolatrexed dihydrochloride |
Description | Nolatrexed dihydrochloride (Thymitaq) is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrexed occupies the folate binding site of thymidylate synthase, resulting in inhibition of thymidylate synthase activity and thymine nucleotide synthesis with subsequent inhibition of DNA replication, DNA damage, S-phase cell cycle arrest, and caspase-dependent apoptosis. This agent also exhibits radiosensitizing activity. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : >10 mM, Sonication is recommended. |
Keywords | Thymidylate Synthase | Thymidylate synthase | RNASynthesis | RNA Synthesis | Nolatrexed Dihydrochloride | Nolatrexed dihydrochloride | Nolatrexed | Inhibitor | inhibit | DNASynthesis | DNA Synthesis | AG-337 | AG337 |
Inhibitors Related | 5-Fluorouracil | Procaine | Rifaximin | Ribavirin | Guanidine hydrochloride | Trimethoprim | N-Nitrosodiethylamine | Cytarabine | Acyclovir | Thymidine | Temozolomide | Folic acid |
Related Compound Libraries | Apoptosis Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$180.00/1kg |
Hebei Zhuanglai Chemical Trading Co.,Ltd
|
2024-06-03 | ||
$339.00/1kg |
VIP5Y
|
Shanghai UCHEM Inc.
|
2023-11-16 | |
$1.00/1kg |
VIP5Y
|
RongNa Biotechnology Co.,Ltd
|
2024-03-26 | |
$15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-08-11 | ||
$1.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-01-28 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY