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Postion:Product Catalog >Nebentan potassium
Nebentan potassium
  • Nebentan potassium

Nebentan potassium NEW

Price $84 $198 $328
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-15

Product Details

Product Name: Nebentan potassium CAS No.: 342005-82-7
Purity: 98.92% Supply Ability: 10g
Release date: 2024/11/15

Product Introduction

Bioactivity

名稱Nebentan potassium
描述Nebentan potassium (YM598) is an orally active and selective nonpeptide endothelin receptor (ETA receptor) antagonist.Nebentan potassium inhibits pulmonary arterial hypertension and may be useful in the study of neurologic and cardiovascular diseases.
體外活性Nebentan potassium also inhibited endothelin-1-induced vasoconstriction in isolated rat aorta with a pA(2) value of 7.6[1].
體內(nèi)活性In medullary rats, the DR(2) values of Nebentan potassium are 0.53 mg/kg and 0.77 mg/kg, respectively. When administered orally at 1 mg/kg, Nebentan potassium maintains its antagonistic effects in conscious rats for over 6.5 hours[1].
存儲(chǔ)條件keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 100 mg/mL (188.82 mM), Sonication is recommended.
關(guān)鍵字Nebentan potassium
相關(guān)產(chǎn)品Macitentan | BMS 182874 | Bosentan | BMS 182874 hydrochloride | Sitaxsentan sodium | Edonentan | Sulfisoxazole | Ambrisentan | Sparsentan | Aprocitentan | Sitaxsentan | Clazosentan
相關(guān)庫疼痛相關(guān)化合物庫 | 經(jīng)典已知活性庫 | 藥物功能重定位化合物庫 | 口服活性化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 | 抗癌化合物庫 | 抗癌活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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