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Postion:Product Catalog >Nebentan potassium
Nebentan potassium
  • Nebentan potassium

Nebentan potassium NEW

Price $84 $198 $328
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-20

Product Details

Product Name: Nebentan potassium CAS No.: 342005-82-7
Purity: 98.92% Supply Ability: 10g
Release date: 2024/11/20

Product Introduction

Bioactivity

NameNebentan potassium
DescriptionNebentan potassium (YM598) is an orally active and selective nonpeptide endothelin receptor (ETA receptor) antagonist.Nebentan potassium inhibits pulmonary arterial hypertension and may be useful in the study of neurologic and cardiovascular diseases.
In vitroNebentan potassium also inhibited endothelin-1-induced vasoconstriction in isolated rat aorta with a pA(2) value of 7.6[1].
In vivoIn medullary rats, the DR(2) values of Nebentan potassium are 0.53 mg/kg and 0.77 mg/kg, respectively. When administered orally at 1 mg/kg, Nebentan potassium maintains its antagonistic effects in conscious rats for over 6.5 hours[1].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (188.82 mM), Sonication is recommended.
KeywordsNebentan potassium
Inhibitors RelatedMacitentan | BMS 182874 | Bosentan | BMS 182874 hydrochloride | Sitaxsentan sodium | Edonentan | Sulfisoxazole | Ambrisentan | Sparsentan | Aprocitentan | Sitaxsentan | Clazosentan
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Orally Active Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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