Product Details
Product Name:
NCGC00092410 |
CAS No.:
442898-34-2 |
Purity:
98.71% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | NCGC00092410 |
Description | NCGC00092410 (ML008) is a glucocerebrosidase (GC) inhibitor with IC50 value of 31 nM. It can be used for the study of Gaucher disease caused by mutation of glucocerebrase gene. |
In vitro | NCGC00092410 increased GC activity in N370S mutant fibroblasts. Treatment of Gaucher's fibroblasts with 40μM NCGC00092410 for 10-70 h increased the lysosomal content of GC in Gaucher's fibroblasts. NCGC00092410 inhibited GC activity with different substrate concentrations in a dose-dependent manner. [1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 5.33 mg/mL (15.09 mM), Sonication is recommended.
|
Keywords | ML 008 | NCGC00092410 | NCGC-00092410 | NCGC 00092410 | ML-008 |
Inhibitors Related | α-Glucosidase-IN-23 | 1-Deoxynojirimycin | Conduritol B epoxide | Voglibose | Pinoresinol diglucoside | Celgosivir | N-Caffeoyl O-methyltyramine | Rebaudioside A | (E)-3-(4-Methoxyphenyl)acrylic acid | IHVR-17028 | Acarbose | 3-Butylidenephthalide |
Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |