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Postion:Product Catalog >Organic Chemistry>Heterocyclic Compounds>Navarixin
Navarixin
  • Navarixin

Navarixin NEW

Price $34 $77 $123
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-14

Product Details

Product Name: Navarixin CAS No.: 473727-83-2
Purity: 98.63% Supply Ability: 10g
Release date: 2024/11/14

Product Introduction

Bioactivity

名稱Navarixin
描述Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophil trafficking in animal models, characteristics that may be beneficial in the treatment of conditions with unbalanced pulmonary neutrophilia.
體外活性Navarixin is a potent, allosteric antagonist of both CXCR1 and CXCR2, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, and 0.08 nM for mouse, rat, and cynomolgus monkey CXCR2, respectively [1].
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 55 mg/mL (138.39 mM), Sonication is recommended.
關(guān)鍵字inhibit | MK 7123 | CXC chemokine receptors | Navarixin | Inhibitor | MK7123 | SCH527123 | CXCR | SCH-527123
相關(guān)產(chǎn)品AZD8309 | rac-NBI-74330 | Delmetacin | Tannic acid | Artemotil | CXCR2-IN-1 | LIT927 | Reparixin | Plerixafor octahydrochloride | Nicotinamide N-oxide | Plerixafor | CXCL-CXCR1/2-IN-1
相關(guān)庫經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抗癌臨床化合物庫 | 藥物功能重定位化合物庫 | 抑制劑庫 | 干細胞分化化合物庫 | 已知活性化合物庫 | GPCR靶點分子庫 | 抗癌活性化合物庫 | 抗癌藥物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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