Description of n-Dodecyl-beta-D-maltoside from Watson Biotechnology Co., Ltd

Specifications(COA) of n-Dodecyl-beta-D-maltoside DDM CAS 69227-93-6 nonionic detergent biochemical and molecular biology research

n-Dodecyl-β-D-maltoside (DDM) is a nonionic detergent commonly used in biochemical and molecular biology research, particularly for the following applications:

1. **Membrane Protein Solubilization**: DDM is frequently used to solubilize and stabilize membrane proteins without denaturing them. It helps to maintain the native structure and function of these proteins, which is crucial for structural studies, including X-ray crystallography, cryo-electron microscopy, and NMR spectroscopy.

2. **Protein Purification**: DDM is used in the purification of membrane proteins through affinity chromatography. The detergent helps to keep the membrane proteins in solution while allowing for their separation and purification.

3. **Structural Studies**: The mild nature of DDM makes it suitable for maintaining the functionality and structure of proteins during various structural analysis methods. It is particularly favored for studying G-protein-coupled receptors (GPCRs) and other membrane-associated proteins.

4. **Enzyme Assays**: DDM can be used in enzyme assays where membrane-bound enzymes are involved. It helps to solubilize the enzyme while preserving its activity, allowing for more accurate activity measurements.

5. **Liposome Preparation**: DDM is also used in the preparation of liposomes or artificial vesicles, which are employed in drug delivery studies, as well as in the study of lipid-protein interactions.

6. **Cell Lysis and Fractionation**: It is used in cell lysis buffers for extracting membrane proteins while preserving the structural integrity of cellular membranes, allowing for the separation of membrane-bound components from the cytosolic fraction.

7. **Crystallization of Membrane Proteins**: In protein crystallization experiments, DDM helps to stabilize the protein in its native form, increasing the chances of obtaining high-quality crystals suitable for X-ray diffraction studies.

Overall, n-Dodecyl-β-D-maltoside is a crucial tool in the study of membrane proteins, where it provides a balance between solubilization efficiency and maintaining protein stability.

Founded in 2006 and headquartered in Wuhan, Hubei, China, Watson Biotechnology Co., Ltd is a leading manufacturing powerhouse specializing in the production of Active Pharmaceutical Ingredients (APIs) and Intermediates, Food and Feed Additives, Agricultural and Aquaculture chemicals, and Fine Chemicals. As a dedicated factory, our operations are driven by a commitment to excellence and innovation, ensuring that our products meet the highest standards of quality and compliance.

With a robust team of over 100 skilled professionals, Watson Biotechnology has established itself as a trusted name in the industry. Our products are meticulously crafted to align with international standards such as USP (United States Pharmacopeia), EP (European Pharmacopoeia), and BP (British Pharmacopoeia), guaranteeing reliability and efficacy.

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Watson Biotechnology Co., Ltd is a professional manufacturer which provide n-Dodecyl-beta-D-maltoside with good quality and best price, welcome to contact us to get COA/TDS/MSDS of n-Dodecyl-beta-D-maltoside.