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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Piperazine compounds>N-Boc-piperazine
N-Boc-piperazine
  • N-Boc-piperazine

N-Boc-piperazine NEW

Price $5 $0.5
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-01-14

Product Details

Product Name: N-Boc-piperazine CAS No.: 57260-71-6
Min. Order: 1KG Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/01/14
Lead time: In stock Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer

1. Materials information

Use of N-Boc-piperazine


N-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

Name1-Boc-piperazine
SynonymMore Synonyms

 N-Boc-piperazine Biological Activity

DescriptionN-Boc-piperazine is a Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker
Target

Alkyl/ether

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Binbin Cheng, et al. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

 Chemical & Physical Properties

Density1.0±0.1 g/cm3
Boiling Point258.0±15.0 °C at 760 mmHg
Melting Point47-49oC
Molecular FormulaC9H18N2O2
Molecular Weight186.251
Flash Point109.8±20.4 °C
Exact Mass186.136826
PSA41.57000
LogP0.55
Vapour Pressure0.0±0.5 mmHg at 25°C
Index of Refraction1.467
Storage conditionRefrigerator

 MSDS



2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: elin@fdachem.com

Mob: 86 13613820652 

WhatsApp/Skype/Wechat/LINE: 86 13613820652


Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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