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Postion:Product Catalog >MYCi361
MYCi361
  • MYCi361

MYCi361 NEW

Price $118 $287 $457
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: MYCi361 CAS No.: 2289690-31-7
Purity: 99.52% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMYCi361
DescriptionMYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).
Animal ResearchFVB or NSG male mice of 6-8 weeks of age and 25 g bearing established MycCaP tumors.MYCi361 treatment i.p. initially at 50 mg/kg twice daily for 2 days, then 70 mg/kg/day for 9 days
In vitroMYCi361 is a small-molecule MYC inhibitors that inhibits the viability of MYC-dependent cancer cells including prostate cancer (MycCaP, LNCaP, and PC3), leukemia (MV4-11), lymphoma (HL-60 and P493-6), and neuroblastoma (SK-N-B2) with low-micromolar IC50 values[1].
In vivoMYC inhibitor 361 (MYCi361), suppressed in vivo tumor growth in mice, increased tumor immune cell infiltration, upregulated PD-L1 on tumors, and sensitized tumors to anti-PD1 immunotherapy.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (168.1 mM), Sonication is recommended.
Keywordsc-Myc | MYCi 361 | NUCC0196361 | MYCi361 | NUCC 0196361 | MYCi-361 | inhibit | Inhibitor | Myc
Inhibitors RelatedBTYNB | MYCMI-6 | VPC-70063 | KJ Pyr 9 | EN4 | Mycro 3 | 10058-F4 | 10074-A4 | ML327 | MYCi975 | 10074-G5 | Nicotinamide N-oxide
Related Compound LibrariesApoptosis Compound Library | Bioactive Compound Library | Glutamine Metabolism Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Wnt/Hedgehog/Notch Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library | Transcription Factor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$118.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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