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Postion:Product Catalog >MRK-740
MRK-740
  • MRK-740

MRK-740 NEW

Price $105 $172 $372
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-12

Product Details

Product Name: MRK-740 CAS No.: 2387510-80-5
Purity: 99.66% Supply Ability: 10g
Release date: 2024/11/12

Product Introduction

Bioactivity

名稱MRK-740
描述MRK-740 is a potent and selective inhibitor of PRDM9 histone methyltransferase.MRK-740 inhibits other histone methyltransferases and inhibits PRDM9-dependent H3K4 trimethylation.
體外活性After 24 hours of treatment, MRK-740 (3 μM) does not affect the growth of HEK293T cells at IC90, but some toxicity is observed at 10 μM. MRK-740 serves as an equivalent inhibitor of H3K4 methylation in MCF7 cells. In cells, MRK-740 selectively and directly inhibits H3K4 methylation at endogenous PRDM9 target sites[1].
存儲(chǔ)條件Shipping with blue ice.
溶解度DMSO : 30 mg/mL (64.58 mM), Sonication is recommended.
相關(guān)產(chǎn)品BIX-01294 trihydrochloride | Tazemetostat | Piribedil | XY1 | UNC 0631 | GSK126 | MAK683 | EZM 2302 | EPZ015666 | AMI-1 free acid | MS37452 | MRTX-1719
相關(guān)庫經(jīng)典已知活性庫 | 表觀遺傳庫 | 抑制劑庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$1520.00/25mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-22
$89.00/1mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-14
$0.10/1kg
VIP2Y
Zibo Hangyu Biotechnology Development Co., Ltd
2024-01-15
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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