Product Details
| Product Name:
MPO-IN-1 |
CAS No.:
2471981-21-0 |
| Purity:
99.27% |
Supply Ability:
10g |
| Release date:
2025/04/27 |
Product Introduction
Bioactivity
| Name | MPO-IN-1 |
| Description | MPO-IN-1 is an orally active myeloperoxidase (MPO) inhibitor, inhibiting MPO and thyroid peroxidase (TPO). It is useful in inflammation research. |
| In vitro | MPO-IN-1 is an irreversible indole-containing myeloperoxidase (MPO) inhibitor with an IC50 of 2.6 μM. [1] |
| In vivo | The plasma concentration of mice was reduced in a biphasic manner after intravenous administration of MPO-IN-1 (1 mg/kg). The mean plasma elimination half-life (T1/2) was 2.6 h. Mpo-in-1 (5 mg/kg or 90 mg/kg orally) causes up-regulation of MPO activity IN the coated exudate in mice. [1] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 160 mg/mL (399.1 mM), Sonication is recommended.
|
| Keywords | MPO-IN-1 | MPOIN1 | MPO IN 1 |
| Inhibitors Related | AZD8309 | ML-210 | RSL3 | ML162 | PF-1355 | 5-Aminosalicylic Acid | Melatonin | 4-POBN | 4-Methylesculetin | Nabumetone | Cefdinir | GSTO1-IN-1 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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