Product Details
Product Name:
Mollugin |
CAS No.:
55481-88-4 |
Purity:
≥95% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Mollugin |
Description | Mollugin (Rubimaillin) may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway. Mollugin as a candidate for a chemotherapeutic agent in OSCCs via the upregulation of the HO-1 and Nrf2 pathways and the downregulation of NF- κ B. Mollugin may be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. Also, it has anticancer efficacy, can modulate the HER2 pathway in HER2-overexpressing Y cells with a potential role in the treatment and prevention of human breast and ovarian Y with HER2 overexpression. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 11 mg/mL (38.69 mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate, Acetone : Soluble
|
Keywords | NF-κB | Mollugin | c-Myc | Nuclear factor-kappaB | Inhibitor | inhibit | Apoptosis | HEK293 | H22-tumor | HepG2 cells | Vascular endothelial growth factor receptor | VEGFR | Reactive Oxygen Species | ROS | HeLa | antitumor | Liver cancer | Hep3B | Myc | DNA damage | anti-hepatocellular | Nuclear factor-κB |
Inhibitors Related | Tucatinib | AG-1478 | (S)-Afatinib | Terodiline | Tannic acid | Afatinib Dimaleate | Neratinib | Cisapride | Pyrotinib dimaleate | AG1557 | Sarizotan 2HCl | VU 0240551 |
Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Selected Plant-Sourced Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
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Suppliers |
Update time |
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$0.00/20mg |
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Shanghai Standard Technology Co., Ltd.
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2019-10-08 |
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$1.00/1KG |
VIP7Y
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Career Henan Chemical Co
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2019-05-25 |
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Shanghai Standard Technology Co., Ltd.
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2019-10-08 |