Product Details
| Product Name:
Mesaconine |
CAS No.:
6792-09-2 |
| Purity:
98% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Mesaconine |
| Description | Mesaconine is an ingredient from Aconitum carmichaelii Debx.. Mesaconine has a cardiac effect and anti-NF-κB activity. Mesaconine may be part of the material basis of Mahuang Fuzi Xixin decoction on anti-inflammation and immune suppression. |
| In vitro | The anti-inflammatory effect of SFI was verified in vitro with endothelial cells. After detecting the cell viability, the expression of interleukin-6 (IL-6), inhibitor of nuclear factor kappa-B kinase (IKK), phosphorylated IKK, phosphorylated NF-κB and phosphorylated IκB-α± from the supernatant were determined. SFI could significantly suppress inflammatory responses, and the mechanism may be via an NF-κB-dependent pathway. Mesaconine is the first reported SFI compounds to have NF-κB inhibitor activity[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (113.27 mM)
|
| Keywords | Inhibitor | inhibit | Mesaconine |
| Inhibitors Related | Lidocaine | Diethylmaleate | Glucosamine | sodium lauroyl-α-hydroxyethyl sulfonate | Lidocaine hydrochloride | L-Arginine | 5-Aminosalicylic Acid | Indole-3-carbinol | Diallyl disulfide |
| Related Compound Libraries | Pyroptosis Compound Library | Anti-Prostate Cancer Compound Library | RO5 Drug-like Natural Product Library | Tibetan medicine Compound Library | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:1235481-43-2
$56.00 / 1mg
-
CAS:872365-14-5
$29.00 / 5mg
-
CAS:2413-38-9
$39.00 / 5mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States