Melanotan ll is an unlicensed and largely untested form of alpha-melanocyte-stimulating hormone, which

causes pigmentation (tanning) of human skin. Melanotan ll is a variant of melanotan I (afamelanotide), a

drug used in the treatment of erythropoietic protoporphyria.

Melanotan ll is not approved for the treatment of any medical conditions currently. It has been reported to

cause a wide range of potentially serious side effects. Warnings against its use have been issued from the

US, UK and several other countries.

How does melanotan ll work?

Melanotan Il non-selectively mimics the action of melanocortin peptides. These are natural hormones

involved with pigmentation, energy homeostasis, sexual functioning, the immune system, inflammation, and

the cardiovascular system. Much like melanotan | (afamelanotide), melanotan ll stimulates the production of

eumelanin, causing the skin to go darker (tanning).

Melanotan lI is usually administered as an injection of liquid underneath the skin, commonly every second

day. Trials have shown that the tanning effect can occur within 5 doses.